Parameter

Capability

System Type

HPLC

Maximum Pressure

Up to 11,600 psi / 80 MPa*

Flow Rate Options

Analytical to preparative configurations

Autosampler Capacity

Up to 108 standard vials

Carryover

<0.0025% under specified conditions

Column Oven Stability

±0.1°C

Cooling

Down to 4°C

Detector Options

UV-Vis, DAD, FLD, RID and other optional detectors

Application Modes

HPLC / 2D HPLC / Semi-Prep HPLC

Parameter

Specification

Pump Configurations

Isocratic, Binary, Quaternary and Dual-Ternary configurations

Gradient Modes

Binary high-pressure, Quaternary low-pressure, Dual-Ternary

Online Degassing

Multiple channel configurations available

Maximum Pressure

Up to 11,600 psi / 80 MPa for HPLC configuration*

Analytical Flow Range

0–5.000 mL/min or 0–10.000 mL/min

Flow Increment

0.001 mL/min

Semi-Preparative Flow Range

Up to 50 mL/min

Preparative Flow Range

Up to 150 mL/min

Pressure Pulsation

≤1.0% at 1 mL/min, water, back pressure >10 MPa

Parameter

Specification

Injection Modes

Full Loop, Partial Loop, Microliter Pick-Up and FTN

Sample Loop Options

10, 20, 50, 100, 1000 and 5000 μL

Standard Sample Capacity

2 × 54 × 1.5 mL vials — 108 positions

Microplate Option

2 × 96-well plates

High-Throughput Option

Up to 216 × 1.5 mL vials or 4 × 96-well plates

Preparative Sample Capacity

2 × 40 × 5 mL vials

Carryover

<0.0025% under specified conditions

Cooling

Optional

Configuration

Repeatability

1000 μL Loop — Full Loop

≤0.3% RSD

1000 μL Loop — Partial Loop

≤0.3% RSD at ≥50 μL

100 μL Loop — Full Loop

≤0.3% RSD

100 μL Loop — Partial Loop

≤0.3% RSD at ≥2 μL

Microliter Pick-Up

≤1.0% RSD under specified conditions

Parameter

Specification

Temperature Control

Forced-air circulation or Peltier control

Heating Range

Ambient +5°C to 90°C

Cooling Range

Down to ambient −21°C, minimum 4°C

Temperature Accuracy

±0.5°C

Temperature Stability

±0.1°C

Column Capacity

Up to 4 × 300 mm columns or multiple shorter columns

Parameter

Specification

Wavelength Range

190–900 nm

Light Source

Deuterium + Tungsten lamps

Wavelength Accuracy

±0.5 nm

Wavelength Precision

±0.1 nm

Parameter

Specification

Wavelength Options

190–640 nm / 190–800 nm

Array

1024 pixels

Spectral Resolution

0.6 nm/pixel

Wavelength Accuracy

±0.6 nm

Wavelength Precision

±0.1 nm

Standard Flow Cell

12 μL, 10 mm optical path

Parameter

Specification

Excitation Range

200–750 nm or 200–900 nm

Emission Range

200–750 nm or 200–900 nm

Light Source

Xenon lamp

Spectral Bandwidth

20 nm

Wavelength Accuracy

±2 nm

Wavelength Precision

±0.2 nm

Water Raman S/N

1200:1

Maximum Sampling Rate

100 Hz

Flow Cell

12 μL

Parameter

Specification

Refractive Index Range

1–1.75

Detection Range

0.25–512 μRIU

Baseline Noise

<2.5 nRIU

Baseline Drift

<200 nRIU/h

Flow Cell Volume

8 μL

Maximum Flow Rate

10 mL/min

Temperature Control

30–60°C

Temperature Accuracy

±0.1°C

Communication

RS-232, RS-485, USB, LAN

Function

Capability

Instrument Control

Pump, autosampler, detector and other module control

Data Acquisition

Integrated chromatographic data acquisition

Data Processing

Automatic integration and adaptive processing algorithms

Audit Trail

Automatic operation records and traceability

User Management

Multi-level user rights

Electronic Signature

Supported

Regulatory Support

FDA 21 CFR Part 11 / GMP / GLP

Database

SQL Server

Reporting

Standard and customizable report templates

Maintenance Reminder

Consumable lifetime tracking and maintenance notifications