UHPLC
Pressure up to 22000 psi
Flexible choices on injection mode
Multiple selection of functions



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High-Pressure UHPLC for Fast, Efficient Separations
A purpose-built UHPLC platform designed for high-pressure separations, flexible injection strategies and demanding analytical workflows.
|
Parameter |
Specification |
|
System Type |
UHPLC |
|
Pump |
Up to 18,000 psi / 124 MPa |
|
Flow Range |
Up to 5.000 mL/min for UHPLC configuration |
|
Injection Modes |
Full Loop / Partial Loop / μL Pick-Up / FTN |
|
Sample Capacity |
Up to 216 × 1.5 mL vials |
|
Carryover |
<0.0025% under specified conditions |
|
Column Oven |
Up to 90°C |
|
Cooling |
Down to 4°C |
|
Detector Options |
UV-Vis / DAD / FLD / RID and other compatible detectors |
The BIKAI 1521 Pro is a dedicated UHPLC platform developed for laboratories requiring higher pressure capability, faster separations and flexible sample handling.
Its high-pressure pump architecture supports modern UHPLC columns and high-efficiency chromatographic methods, while configurable autosampling and temperature-control options allow the system to adapt to different method and throughput requirements.
The modular detector architecture also enables the system to be configured according to the analytical characteristics of the target compounds.
The 1521 Pro can be configured with next-generation UHPLC pump options according to required pressure capability.
|
Parameter |
|
|
Maximum Pressure |
18,000 psi |
|
Pressure Equivalent |
124 MPa |
|
Application |
UHPLC |
· High-pressure binary gradient configuration
· Flow range up to 5.000 mL/min
· Flow increment: 0.001 mL/min
· Online degassing
· Designed for high-pressure UHPLC separations
· Pressure pulsation control for stable chromatographic operation
The 1521 Pro supports multiple injection strategies for both conventional and high-throughput UHPLC workflows.
|
Parameter |
Specification |
|
Injection Modes |
Full Loop / Partial Loop / μL Pick-Up / FTN |
|
Loop Options |
10 / 20 / 50 / 100 / 1000 / 5000 μL |
|
Standard Capacity |
108 × 1.5 mL vials |
|
High-Throughput Capacity |
216 × 1.5 mL vials |
|
Microplate Capacity |
Up to 4 × 96-well plates |
|
Preparative Configuration |
80 × 5 mL vials |
|
Carryover |
<0.0025% under specified conditions |
|
Cooling |
Optional |
|
Injection Mode |
Repeatability |
|
Full Loop |
≤0.3% RSD |
|
Partial Loop |
≤0.3% RSD under specified volume conditions |
|
μL Pick-Up |
≤1.0% RSD under specified conditions |
|
Parameter |
Specification |
|
Temperature Control |
Forced-air circulation / Peltier |
|
Heating Range |
Ambient +5°C to 90°C |
|
Cooling Range |
Down to ambient −21°C |
|
Minimum Temperature |
4°C |
|
Temperature Accuracy |
±0.5°C |
|
Temperature Stability |
±0.1°C |
|
Column Capacity |
Up to 4 × 300 mm columns |
· Automatic switching valves
· PEEK switching valves
· Multiple two-position six-port valve configurations
· Two-position ten-port valve options
· Parallel switching of multiple columns
· Configurations for SPE and multidimensional chromatography
The 1521 Pro can be configured with different detector technologies according to the analytical requirement.
|
Parameter |
Specification |
|
Wavelength Range |
190–900 nm |
|
Light Source |
Deuterium + Tungsten lamps |
|
Wavelength Accuracy |
±0.5 nm |
|
Wavelength Precision |
±0.1 nm |
|
Parameter |
Specification |
|
Wavelength Options |
190–640 nm / 190–800 nm |
|
Array |
1024 pixels |
|
Spectral Resolution |
0.6 nm/pixel |
|
Wavelength Accuracy |
±0.6 nm |
|
Wavelength Precision |
±0.1 nm |
|
Standard Flow Cell |
12 μL, 10 mm optical path |
|
Low-Volume Option |
2 μL, 10 mm optical path |
|
High-Sensitivity Option |
12 μL, 60 mm optical path |
|
Parameter |
Specification |
|
Excitation Range |
200–750 nm or 200–900 nm |
|
Emission Range |
200–750 nm or 200–900 nm |
|
Light Source |
Xenon Lamp |
|
Water Raman S/N |
1200:1 |
|
Sampling Rate |
100 Hz |
|
Flow Cell |
12 μL |
|
Parameter |
Specification |
|
Refractive Index Range |
1–1.75 |
|
Baseline Noise |
<2.5 nRIU |
|
Baseline Drift |
<200 nRIU/h |
|
Flow Cell Volume |
8 μL |
|
Maximum Flow Rate |
10 mL/min |
|
Temperature Control |
30–60°C |
|
Temperature Accuracy |
±0.1°C |
The BIKAI ChromCore chromatography workstation provides integrated instrument control, acquisition, processing and reporting.
|
Function |
Capability |
|
Instrument Control |
Pump, autosampler, oven and detector control |
|
Data Acquisition |
Integrated chromatographic acquisition |
|
Data Processing |
Automatic integration and data-processing algorithms |
|
Audit Trail |
Traceable operation records |
|
User Management |
Multi-level permissions |
|
Electronic Signature |
Supported |
|
Regulatory Support |
FDA 21 CFR Part 11 / GMP / GLP |
|
Reporting |
Standard and customizable reports |
|
Maintenance Management |
Consumable-life and maintenance reminders |
Have questions or want to learn more? We’d love to hear from you.